Engine Compartment Fuse Box
The engine compartment fuse box is in the engine compartment. It has high-current fuses that protect your vehicle’s main electrical systems from overloads.If you disconnect and reconnect the battery, you need to reset some features.
Note: If your vehicle has dual batteries, disconnecting the primary under hood battery does not remove power from all circuits.

| Fuse Number | Fuse Rating | Protected Component |
|---|---|---|
| 1 | 20 A | Horn. |
| 2 | 50 A | Blower motor. |
| 3 | — | Not used. |
| 4 | 30 A | Starter relay. |
| 5 | 20 A | Not used (spare). |
| 6 | 20 A | Upfitter relay 4 (cutaway). Not used (spare) (stripped chassis). |
| 8 | — | Not used. |
| 10 | — | Not used. |
| 12 | 20 A | Power point 4. |
| 13 | 10 A | Yaw sensor (stripped chassis). Not used (spare) (cutaway). |
| 14 | 10 A | Forward looking radar (cutaway). Not used (spare) (stripped chassis). |
| 15 | — | Not used. |
| 16 | — | Not used. |
| 17 | 10 A | Powertrain control module run/start feed. |
| 18 | 10 A | Anti-lock brake system run/start feed. |
| 19 | — | Not used. |
| 20 | 30 A | Wiper power. |
| 21 | — | Not used. |
| 22 | 10 A | Wiper module (stripped chassis). Not used (spare) (cutaway). |
| 23 | — | Not used. |
| 24 | 40 A | Body control module – run power in feed 2. |
| 25 | 50 A | Body control module – run power in feed 1. |
| 26 | — | Not used. |
| 27 | 20 A | Body builder frame connector. |
| 28 | — | Not used. |
| 29 | 10 A | B+ power 12 V (special order vehicle). |
| 30 | 30 A | Power driver seat (cutaway). Not used (spare) (stripped chassis). |
| 31 | — | Not used. |
| 32 | 20 A | Vehicle power 1. |
| 33 | 20 A | Vehicle power 2. |
| 34 | 10 A | Vehicle power 3. |
| 35 | 20 A | Vehicle power 4. |
| 36 | — | Not used. |
| 37 | — | Not used. |
| 38 | 10 A | Washer relay (stripped chassis). Not used (spare) (cutaway). |
| 39 | — | Not used. |
| 41 | 30 A | Trailer brake control connector. |
| 43 | 30 A | Instrument panel connector (stripped chassis). Not used (spare) (cutaway). |
| 45 | — | Not used. |
| 46 | 10 A | A/C clutch. |
| 47 | 40 A | Upfitter relay 1 (cutaway). Not used (spare) (stripped chassis). |
| 48 | — | Not used. |
| 49 | 30 A | Pump electronics module. |
| 50 | 15 A | Injectors. |
| 51 | 20 A | Power point 1. |
| 52 | 50 A | B-pillar vehicle connector (cutaway). Not used (spare) (stripped chassis). |
| 53 | 30 A | Trailer tow park lamps. |
| 54 | 40 A | Upfitter 2 relay (cutaway). Not used (spare) (stripped chassis). |
| 55 | 20 A | Upfitter 3 relay (cutaway). Not used (spare) (stripped chassis). |
| 56 | 20 A | Power point 2 prep B-pillar connector. |
| 58 | 5 A | USB smart charger. |
| 59 | 10 A | Park lamps 1 (special order vehicle). |
| 60 | — | Not used. |
| 61 | — | Not used. |
| 62 | — | Not used. |
| 63 | — | Not used. |
| 64 | — | Not used. |
| 65 | — | Not used. |
| 66 | — | Not used. |
| 67 | — | Not used. |
| 69 | — | Not used. |
| 70 | 40 A | Inverter. |
| 71 | 30 A | Anti-lock brake system valves. |
| 72 | 10 A | Brake on and off switch. |
| 73 | — | Not used. |
| 74 | — | Not used. |
| 75 | — | Not used. |
| 76 | 60 A | Anti-lock brake system pump. |
| 77 | 30 A | Voltage quality module power – body control module. |
| 78 | 10 A | Trailer tow stop lamps. |
| 79 | — | Not used. |
| 80 | 10 A | Trailer tow backup lamps. |
| 81 | — | Not used. |
| 82 | 5 A | Run/start fuse – upfitter relays (cutaway). B+ fuse – upfitter relay. |
| 83 | — | Not used. |
| 84 | — | Not used. |
| 85 | — | Not used. |
| 86 | — | Not used. |
| 87 | — | Not used. |
| 88 | — | Not used. |
| 89 | — | Not used. |
| 91 | 40 A | B-pillar (cutaway). Instrument panel (stripped chassis). |
| 93 | 10 A | Park lamps 3 (special order vehicle). |
| 94 | 10 A | Park lamps 2 (special order vehicle). |
| 95 | 20 A | Stop lamp relay. |
| 96 | — | Not used. |
| 97 | 50 A | Engine. B-pillar vehicle connector. Instrument panel. |
| 98 | 30 A | Trailer tow battery charge. |
| 99 | 40 A | Instrument panel connector. |
| 100 | — | Not used. |
| 101 | — | Not used. |
| 102 | — | Not used. |
| 103 | — | Not used. |
| 104 | — | Not used. |
| 105 | 15 A | Trailer tow right-hand and left-hand stop and direction indicator relay power. |
Note: Spare fuse amperage may vary.
| Relay Number | Fuse Rating | Protected Component |
|---|---|---|
| R02 | — | Powertrain control module. Power relay. |
| R05 | — | Not used. |
Passenger Compartment Fuse Box
The fuse panel is to the left-hand side of the brake pedal and mounted onto the lower left-hand cowl panel.To remove a fuse, use the fuse puller tool provided on the inside of the fuse panel cover.Replace fuses with the same type and rating. See Changing a Fuse .
Note: If your vehicle has dual batteries, disconnecting the primary under hood battery does not remove power from all circuits.

| Fuse Number | Fuse Rating | Protected Component |
|---|---|---|
| 1 | — | Not used. |
| 2 | 10 A | Left-hand front and right-hand front door lock switch (cutaway). Inverter (cutaway). Connector (stripped chassis). |
| 3 | 7.5 A | Power mirror switch (cutaway). |
| — | Not used (stripped chassis). | |
| 4 | 20 A | Trailer brake control. |
| 5 | 20 A | Not used (spare). |
| 6 | 10 A | Not used (spare). |
| 7 | 10 A | Not used (spare). |
| 8 | 10 A | Not used (spare). |
| 9 | 10 A | Not used (spare). |
| 10 | — | Not used. |
| 11 | — | Not used. |
| 12 | 7.5 A | Smart datalink connector. Enterprise wired-in-device. |
| 13 | 7.5 A | Cluster. Steering column control module. |
| 14 | 15 A | Not used (spare). |
| 15 | 15 A | Not used (spare). |
| 16 | — | Not used. |
| 17 | 7.5 A | Not used. |
| 18 | 7.5 A | Climate mode switch. |
| 19 | 5 A | Radio transceiver module. |
| 20 | 5 A | Ignition switch. |
| 21 | 5 A | Not used. |
| 22 | 5 A | Body builder B-pillar connector (cutaway). |
| 5 A | Not used (stripped chassis). | |
| 23 | 30 A | Not used (spare). |
| 24 | 30 A | Not used (spare). |
| 25 | 20 A | Not used (spare). |
| 26 | 30 A | Not used (spare). |
| 27 | 30 A | Not used (spare). |
| 28 | 30 A | Not used (spare). |
| 29 | 15 A | Upfitter interface module (cutaway). |
| — | Not used (stripped chassis). | |
| 30 | 5 A | Not used (spare). |
| 31 | 10 A | Smart datalink connector. |
| 32 | 20 A | Radio. |
| 33 | — | Not used. |
| 34 | 30 A | Not used (spare). |
| 35 | 5 A | Tow haul switch. |
| 36 | 15 A | Rear view mirror (cutaway). Rear view camera (cutaway). |
| — | Not used (stripped chassis). | |
| 37 | 20 A | Not used (spare). |
| 38 | 30 A | Rear window switches and motors (cutaway). |
| — | Not used (stripped chassis). |
Note: Spare fuse amperage may vary.
2021 Ford E-350 Owners Manual
Changing a Fuse
Fuses
If electrical components in the vehicle are not working, a fuse may have blown. Blown fuses are identified by a broken wire within the fuse. Check the appropriate fuses before replacing any electrical components.Fuse Types
| A B C D E F G H |